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One very small study found that people who used semaglutide had lower B12 levels, but these patients also had bariatric surgery prior to using semaglutideso its hard to say if using semaglutide would lead to a B12 deficiency, requiring additional B12

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Boosting it could extend healthy lifespan."[13][3] He advocates for precursors but sees value in inhibitors like 5-Amino-1MQ to maximize NAD+ utility